The artemisin based-therapeutic combinations (ATC) are an approach developed to solve the malaria parasite chemo-resistance problem in endemic area. The aim of this study is to evaluate the factors associated to the weak proportion of children under the age of 5 years treated with the ATC against malaria. The data collected on a sampling of 9177 treated children in 13 health centers in Gbado-Lite city in 2014 have been analyzed with the help of Epi-info software package (version 3.5.4). The number of children treated with the ATC is weak (58.9%) in spite of the availability in ATC (87.7%). The socio-demographic factors and the life styles of the ATC prescribers are not associated to the weak proportion of the children treated with ATC (p>0.5). Nevertheless, a strong non-significant association is observed with alcohol consumption by the prescribers of ATC (p>0.72). A weak non-significant association is noted in male (p=0.52) and with the seniority of the prescribers (p=0.71). The factors like age, marital status, monthly income, study level, lodging and consumption of tobacco are not associated with the weak proportion of children treated with ATC. The influence of the number of staffs working in the health centers on the proportion of children treated with ATC is variable according to the considered structures of health. It is therefore desirable to develop advantage of the strategies for a rational prescription in order to guarantee a better malaria treatment in children at Gbado-Lite city.
The bioaccumulation of four heavy metals (Zn, Pb, Cu and Cd) in Clarias gariepinus (Burchell, 1822), Chrysichthys nigrodigitatus (Lacepède, 1803), Mormyrops anguilloides (Linnaeus, 1758) and Coptodon rendalli (Boulenger, 1897) fluently fished and sold in Kingabwa district (Kinshasa, Democratic Republic of the Congo). At first, the results of physico-chemical analysis of water of inspected sites (2) revealed that the values of pH and temperature are in the standards as recommended by WHO and FAO, while the conductivity as well as the dissolved total solids in inspected sites are very weak.. Yet, the two sites are polluted by heavy metals. Secondly, the dosage of heavy metals by atomic absorption spectrometry revealed that all tested fish are polluted. However, the Cadmium has not been detected in the muscles of three fish: Clarias gariepinus, Coptodon rendalli and Mormyrops anguloides. Meanwhile, Coptodon rendalli species didn't reveal any presence of Lead in its muscles. The results obtained show that the consumption of these fish can represent a health risk for the exposed populations notably fishers and their family who consume these fish at least once per day. Thus, by formulating the hypothesis that the fisher or his family is the more exposed and while increasing the quantity of fish for example from 0.025 kg/j to 0.5 kg/j, we can note that the coefficient of danger is superior to 1 for the cadmium and then the danger becomes apparent. It is therefore desirable that the Democratic Republic of the Congo authorities can develop a better policy for the management of the interior waters in order to avoid possible health problems linked to the pollutions of these waters.