The objective of our study is to analyse the different bacteriological profiles and their antibiotic sensitivity patterns of bacterial keratites in our bacteriology laboratory at the Hassan II University Hospital in Fez.A retrospective study carried out at the bacteriology laboratory of the Hassan II University Hospital of Fez over a period of 3 years from 01/01/2018 to 31/10/2020 in patients diagnosed with infectious keratitis and who have benefited from a corneal sample + culture for bacteriological study. Demographic data, clinical characteristics, bacteriological data and antibiotic resistance and sensitivity were collected.Out of 218 corneal swabs, bacteria were isolated from 123 samples (56.4%). The most frequent isolates were coagulase-negative Staphylococci (SCN) (51.5%), Staphylococcus aureus (22.2%) and Pseudomonas aeruginosa (14.2%). All gram-positive isolates were susceptible to vancomycin, but methicillin resistance was found in 36.9% of CNS cases and no cases of MRSA were recorded. All gram-negative isolates were susceptible to ceftazidime, gentamicin, tobramycin and amikacin. Resistance to ciprofloxacin was observed in 20% of the gram-positive isolates.CNS, Staphylococcus aureus and Pseudomonas aeruginosa were the microorganisms most often responsible for bacterial keratitis. Dual therapy using vancomycin + ceftazidime should be considered for empirical treatment until culture and susceptibility results are available in order to adapt antibiotic therapy.