This research explores the perceptions of the inhabitants of Bunia on the use of depigmenting cosmetic products. The qualitative research design using ethnographic method was used to conduct this study. Semi-structured interview was used to carry out this study with a sample of 80 participants, chosen by occasional sampling. After analysis, the study revealed that the main reasons for the use of depigmenting consmetic products were the desire to achieve a clearer complexion and to improve one’s appearance, influences marked by social norms and the media. Some users also use it for therapeutic purposes, in particular to treat skin problems such as acne. The analysis reveals a preference for several types of product. Milks and lotions top the list, followed by injections and tablets, while depigmenting soaps are still widely used. Although some people believe that men and women use depigmenting products equally, the practice is still predominantly female. Participants expressed deep concern about the associated health risks: skin cancers, medical complications, unpleasant body odours and irregular pigmentation problems. In view of these results, it is vital to adopt a multidisciplinary approach, by stepping up targeted awareness-raising campaigns, using innovative approaches, but also by ensuring regulation, banning the most harmful products and promoting greater individual awareness of the risks.