Azagny National Park, is only coastal park in Côte d’Ivoire classified a zone RAMSAR. However, It is subject to strong degradation. The most common causes are peripheral agriculture, harverting of non-timber and wood forest products. All these factors lead to the increase of tracks, and therefore of ruderal areas, which facilitate the establishment, abundance and proliferation of invasive plants. These species are among the greatest threats to the integrity of protected areas and their struggle is a challenge. It is therefore necessary at first to know the ruderal flora of the park which is hitherto little known, to determine the invasive plants present in the park. The general objective of this study to improve knowledge of the flora and vegetation of the ruderal areas of Azagny national park. To achieve this objective, floristic inventory was carried in 92 plots of 50 m2 (5m x 10m) equidistant from 300m. The plant species were inventoried taking into account their abundance-dominance. The flora contains 150 species. 18 species with a particular status were inventoried. Ruderal areas of the park are home 15 invasive plants, including ten proven invasive plants, four potential ivasive plants and one species to monitor. Phytosociological study identified three plant groups including one of which were colonized by invasive plants. It is necessary to put in place a strategy and an action plan for these invasive plants in order to avoid the possible evolution in this forest heritage.