The influence of combination of agricultural product (rice bran)/fertilizer (goat dropping and manner NPK-17-17-17) was tested within 9 months in growing performances of Nile tilapia, bred in semi-drained pond. The mean results showed that the parameters of aquatic environment, in particularly temperature (29°C - 36°C) and pH (5.5 – 6.5), fluctuate in the tolerance limits of Nile tilapia. Growing performances are interesting: Rice bran combined with mineral or organic fertilization profit well to Nile tilapia growing with 0.42g/day of weight advantage against 0.29g/day for the witness. It is the same for yield which is 1.8 times and 1.7 times more the witness, about an increasing of 80.5 and 67.6% of natural productivity, respectively for NPK-17-17-17 and organic fertilizer goat dropping-based.