A zooplankton production trial based on chicken manure and guinea pig droppings was conducted between July and August 2014 at the Dschang University Research and Application Farm to contribute to the improvement of the productivity of fish farming systems. This work was aimed at determining the period and the best fertilizer to produce some zooplankton of interest necessary for larval rearing. An experimental design of 2 treatments and one control (unfertilized): T1 (chicken manure), T2 (guinea pig droppings) at a rate of 2.13 kg /are each triplicate was used in a completely Randomized 9 basins of 1 m3 previously inoculated with copepods and rotifers at densities of 14 and 45 ind / l of water respectively. Physico-chemical parameters of water and biological (zooplankton) follow-up was done every 2 days and the collected data were submitted to a one-way analysis of variance. It follows that: Except for temperature, pH and water depth, fertilizers had a significant effect on the physico-chemical characteristics of the water (p < 0.05). The most significantly high zooplankton densities (1161 ± 15 ind / l) (p <0.05) as well as rotifer and copepod species were obtained on day 12 and day 20 in basins fertilized with chicken manure, on the 14th and 22nd day for those fertilized with Guinea pig’s droppings. The highest densities, biomass, daily production and intrinsic growth rates of the copepods were observed in basins fertilized with guinea pig droppings. Each of the fertilizers has been shown to be of interest to produce a specific type of zooplankton, guinea pig droppings for copepods and chicken manure for rotifers.