The work depends on the development of a wheelchair that can be a fully automatic navigation system. It provides flexible operation to choose different modalities to command the wheel chair, this method is very useful to a people who can affected for charcot-marie-tooth disease. Patients can command the wheelchair based on their eye blinks, eye movement. The wheelchair can operate like an auto-guided vehicle, following IR sensor way. The digital commends from the IR sensor is moved to raspberry pi. It provides commands to be sent to the wheelchair. Several experiments are used in this technique to introduce an effective wheelchair for disabled persons.