The determinants that influence the mode of disposal of household solid waste were studied in the cities of Parakou, Djougou, Kandi and Malanville in northern Benin. Sex, age, educational level, marital status, income, household size, socio-professional category, type of neighborhood, type of habitat, cities are the variables taken into account and analyzed by the Chi2 test and logistic regression. The results showed little overall trend varies from one city to another household to evacuate their garbage directly in nature (χ2 = 1.188; DF = 3; P-Value = 0.756> 0.05). Moreover, no statistically significant association was detected between the mode of waste disposal and sex (χ2 = 1.267; DF = 3; P-Value = 0.737> 0.05), age of household heads (χ2 = 2.868; DF = 4; P-Value = 0.580> 0.05), marital status (χ2 = 7.710, DF = 9; P-Value = 0.564> 0.05); household size (χ2 = 4.688; DF = 3; P-Value = 0.196> 0.05). In the cities studied, only in Parakou, χ2 = 18.275; DF = 7; P-Value = 0.011 <0.05 and Djougou, χ2 = 17.108; DF = 9; P-Value = 0.047 <0.05, very significant links were found between the mode of waste disposal and the occupational category of household heads. Note also that no relationship was statistically observed between the mode of waste disposal and the level of heads of household income in Djougou, χ2 = 3.909; DF = 4; P-Value = 0.418> 0.05); Kandi, χ2 = 2.826; DF = 3; P-Value = 0.419> 0.05) and Malanville, χ2 = 2.482; DF = 3; P-Value = 0.479> 0.05). But in the four cities, 100% very highly significant association was observed between link waste disposal and education level of household heads at the global level (χ2 = 28.328; DF = 3; P-Value = 0.000 <0.05). Logistic regression analysis also revealed a strong correlation between educational level (χ2 = 9.439; DF = 3; P-Value = 0.024 <0.05 and mode of waste disposal in North Benin.