The management of the issue of medical and pharmaceutical waste is embarrassing to many countries. Morocco does not escape this reality. Since the first circular in 1991, Morocco has developed the legal arsenal because they pose risks to health and environment. The objective of our study is to characterize the risk of bacteriological solid waste of care units in Mohamed V hospital. The sample includes five Care units with significant waste production: intensive, the burnt, the Emergent, the Respiratory and central operating room. This hospital is a regional focus with a bed capacity of 388 and serves a population of 2 186 000 citizen. Twice, it won the first prize of quality competition organized annually by the Ministry of Health. We advocated as methodology the analysis samples in medical laboratory. The samples are as follows: Ten samples from the Medical waste before treatment at ECODAS T300 grinder and five after theme treatment. Pathogens were obvious from the analysis before the treatment, which is normal. However, an alarming point is their persistence even after treatment with the grinder. These results raise the question of the effectiveness of treatment systems by grinding in general and in particular for ECODAS T300: which it is designed for sterilization (complete destruction of germs) or simply for disinfecting (reduction of microbial burden)?