The ligand glycine-2-hydroxy-1-naphthaldehyde (GNH) was synthesized by stirring at room temperature and used for the preparation of Mn(II), Co(II) and Zn(II) complexes. These were characterized using infrared, electronic absorption data, molar conductivity melting points and solubility. The melting points of the synthesized compounds were in the range of 235.6- 253.7 0C while the conductivities measured in DMSO were in the range of 2.09 - 6.65 µs. The infrared spectra data of these ligands and their metal complexes showed that the ligands are neutral bidentate molecules which coordinated to the metal ions through the azomethine nitrogen atom of the Schiff bases and the carboxylate oxygen atom of the schiff bases. From the UV visible data available, tetrahedral geometry have been assigned to the prepared complexes. The antimicrobial studies of the synthesized compounds on micro-organisms such as: Escherichia coli, Staphylococus aureus, Salmonella typhi and Candida albicans at different concentrations revealed that all the ligands and complexes have good antimicrobial activities. The complexes showed enhanced activities and their activities against the micro organisms increased with increasing concentrations.