Soil nutrient analysis is crucial for understanding the dynamics of agricultural fertility and productivity. Phosphorus (P) stands out among soil nutrients for its fundamental role in vital biological processes such as photosynthesis, respiration, and cell division. The study of variations in phosphorus content along toposequences, according to the specific topography of the lowlands, is proving to be a relevant approach to elucidate the complex interactions between abiotic factors and biogeochemical dynamics that govern soil fertility. This study aims to characterize spatial variations in soil assimilable phosphorus (P2O5) content as a function of edaphic parameters, using a multidimensional approach along the longitudinal and transverse axes of the lowland. This study was carried out in the locality of N’Zoupouri, in the department of Botro, about 40 km from Bouaké, in the Gbêkê region of central Côte d’Ivoire. The physicochemical analyses of the soil samples were carried out by French and international standard methods. The BORUTA algorithm used in this study can select the truly significant characteristics while ranking their importance. The result shows that potassium (K) content is a determining factor directly influencing this essential nutrient’s spatial variations and temporal changes. The close relationship between potassium and phosphorus in the soil highlights the importance of optimized agronomic management, in which potassium not only plays a supporting role but also acts as a key element in the release and stabilization of phosphorus that is available to plants.