Objectives: assess the level of knowledge, attitudes and practices of health personnel in the Sangalkam Health District on blood exposure accidents. Methodology: We conducted a cross-sectional, descriptive and analytical study, from April 1, 2023 to May 30, 2023. A standardised, anonymous questionnaire was drawn up and sent to healthcare staff. Results: A total of 60 carers took part in the study, 88.3% of whom were women. Midwives were more represented (31.7%). Hepatitis B vaccination coverage was 69.6%. 31.7% of respondents were aware of the viruses most feared in the event of a blood exposure accident (HIV, HBV and HCV). They claimed to know the principles of universal precaution in 91.5% of cases. The prevalence of blood exposure accidents was 61.7%, i.e. 27% reported. Washing with soapy water was carried out immediately after the BEA in 56.8% of cases. Needles were recapped by 28.3% of respondents. Where there was a risk of splashing of biological fluid, personal protective equipment (gown, mask, goggles) was worn by 23.3% of respondents. Overloading of safety containers was reported in 11.7% of cases. Respondents’ knowledge and attitudes were not significantly related to socio-professional characteristics (p>0.05). Conclusion: Compliance with standard precautions and the use of safety equipment could significantly reduce the risks associated with AES. In addition, awareness-raising and vaccination of healthcare workers against hepatitis B should be encouraged.