Objectives: Analyze MSDs among workers of the National Electricity Company of Senegal. Methodology: This was a cross-sectional, descriptive and analytical study, carried out from April 2 to May 15, 2022. The INRS TMS questionnaire version 2000 was used. The analysis was carried out with Excel 2016 and R version 4.1.1 software. During the bivariate analysis, the Chi2 test was used. The p was considered significant if it was less than 0.05. Results: The average age of the sample was 42.4 years ± 9.5. The sex ratio (M/F) was 3.16 in favor of men. The prevalence of MSDs was 91%. The average number of MSD locations per affected worker was 3.1. Low back pain (58.8%) and back pain (54.2%) were the most frequently reported MSDs. When working, the sitting position and prolonged standing position were adopted respectively by 57.7% and 39.4% of workers. Break time, work requiring work very quickly, work under deadline, risk of error in work in the event of lack of concentration and the latitude of being able to work at the desired speed had a significant link with occurrence of MSDs (p<0.05). Conclusion: MSDs constitute an occupational health problem within the National Electricity Company of Senegal. This study proves the need to strengthen, on the one hand, awareness, training of workers and on the other hand, the review of the organization and management of personnel.