This quantitative article aims to evaluate the influence of absenteeism on the performance of health care personnel in Chad. It is based on a sample of 399 subjects from the public service, civil servants, state contractuals and institutional contractuals, aged between 18 and 50 years, male and female, married, widowed, divorced or single. The data collection was done through a questionnaire and the structural equation analysis is the method used. The results show that absenteeism negatively influences the performance of health care personnel Chad.