The dental prosthesis is defined as an artificial device intended to replace the missing tooth or teeth and the related tissues. Clinical reality places us in front of an infinite dental edentation situation. For the rehabilitation of missing teeth, it is often necessary to manage simultaneously the use of all prosthetic techniques: partial and total prosthesis, fixed prosthesis and implantology.The aim of this investigation is to evaluate dental prosthesis needs in the University Hospital of Odonto-Stomatology of Bamako (CHUOS).A survey was conducted at Bamako University Hospital over a period of one month. The study included 400 patients who consulted for making dental prosthesis. Patients with 1-4 teeth to replace in the maxillar represented 30, 1% of cases and 30,7% in the mandible. The results showed the highest rate concerning partial removable denture prosthesis preference (83%) in comparison with fixed prosthesis which represented only 8, 75% of cases. Also, the partial removable prosthesis was diagnosed in 52,25% of cases.Edentation can be the cause of several problems in the oral cavity, hence the need to sensitize the population of the importance of oral health and the importance of wearing the prosthesis in case of losing teeth.