Introduction: The uterine adenosarcome is a rare tumor, is composed of a benign glandular component and a sarcomatous stroma. It’s characterized by its rarity, difficulties in both diagnostic and therapeutic care. Patients and methods: A retrospective review, from 1993 to 2013, of five cases of uterine adenosarcome diagnosed and treated at the institute Salah Azaeiz. Results: Patients’ mean age was 54.4 years. Three patients were postmenopausal. Vaginal bleeding was the most common presenting symptom. Physical examination combined with pelvic ultrasonography found a uterus increased in size. The diagnosis was made by biopsy curettage, biopsy of the polyp or study of the surgical specimen. Three patients underwent surgery. Four patients were in FIGO stage I, one patient in stage IV. Two patients benefited from adjuvant radiotherapy and one patient benefited only from chemotherapy. After a mean follow-up of 54 months, one patient was in complete remission. Pelvic local recurrence and metastasis in inguinal nodes were observed in two patients. Conclusion: Surgery is often sufficient. Its prognosis is relatively favorable.