The present study aims to: (i) check its abundance and distribution Sterculia setigera Del. in Togo according to biophysical factors and (ii) forecast its potential suitable habitat. S. setigera trees (DBH ≥ 10 cm) were numbered and human activities were recorded within 518 plots. Geographic Information System offers applications for evaluation of the abundance in relation to anthropogenic threats, human population density, elevation, annual mean temperature, annual mean precipitation, and types of soils. The distribution model based on Maximum Entropy was used to forecast the potential suitable habitat using the species occurrence data and environmental data. Occurrence data were gathered from fieldworks, herbarium records, and scientific published papers. Environmental data were formed by 19 bioclimatic variables and altitude data. Based on cross-correlations among variables, variables’ contribution, and jackknife test of variables’ importance, six bioclimatic variables were selected for model running. The two main variables that contributed towards predicting the potential suitable habitat were the annual precipitation and the temperature seasonality. The abundance of the species is more positively correlated by the soil type and the topography while it is negatively correlated to rainfall. Anthropogenic threats’ importance increase from the south to the north of the country while human population density decrease. The most suitable habitat of S. setigera were predicted in eco-floristic zones I and III of Togo. Further studies on the nursery, the regeneration, the cultivar selection and the assessment of the future climate impact will be a great asset for its sustainable management and domestication.