The aim of this study is to reveal antioxidant capacity of methanol extract of Origanum haussknechtii aerial parts. The antioxidant capacity of methanol extract were assayed with various methods, metal chelating capacity, DPPH free radical and ABTS radical cation scavenging activity, including total phenolic compound contents by Folin – Ciocalteu reagent (FCR). The obtained results were compared with standard antioxidants such as Ascorbic acid, BHT and EDTA. The methanol extract of O.haussknechtii aerial parts showed free radical scavenging activity similar to that of BHT. Also, this extract exhibited strong ABTS radical cation activity. As a conclusion of this study, the methanol extract of O.haussknechtii has beneficial effects on metal chelating, ABTS radical cation , DPPH radical scavenging abilities and may thus exert protection against oxidative damage.