While a lot of studies in the past proved the relation of personality type to brain dominance, studies now tend to disprove the association of such variables. With this trend in research, the researcher was challenged to conduct an investigation in educational setting, taking into consideration the correlation of learners' brain dominance and mathematics performance.The brain dominance characterized by Left Right Brain Dominance Test and grades in Algebra and Trigonometry were elicited from the sample student-respondents. The coefficient of variations and coefficient of correlations were computed to scientifically examine the extent of correlation of the chosen variables. Findings disclosed that there were a smaller number of left-brain dominant learners with a smaller variation in the mathematics performance. Moreover, there were no significant correlations found between the learners' brain dominance and their performance in mathematics. The non-significance in correlation may be explained by the insights yielded from previous researches that (1) learners do have different personalities and have unique strengths and weaknesses in how they process information; and (2) personalities and abilities of learners are not determined by favoring one hemisphere over the other, but both hemispheres are used by learners in thinking processes. The opposing opinions revealed by several researchers can be taken positively as a challenge in the educational environment, specifically for learners and teachers.