This paper presents the concentration of Cu, Zn, Fe, Pb and Cd in vegetables, soil and water samples. Samples were collected from Mayham (Adigrat, Tigray region). Total acid (7ml mixture of HNO3, H2SO4, HClO4) digestion method was employed and determination was made by flame atomic absorption spectroscopy. The percentage recoveries of the metals were in the range of 89% to 100% in vegetable, 84% to 100% in water and 82% to 103% in soil sample. The range of concentration(µg/g) of the metals on dry weight basis are: Cd 1.18-1.45 in vegetables, 1 in soil and 9 in water; Cu 9-18 in vegetables, 15-17 in soil and 4.3 in water; Pb 1.67-5.01 in vegetable, 3-5 in soil and 2.6 in water; Zn 40-398.5 in vegetable, 59-66.8 in soil and 9.2 in water; Fe 218.25-4987.5 in vegetables, 23705.75 – 29248.5 in soil and 177.5 in water sample. The result obtained imples that the plant is rich in iron, zinc and copper and has small concentration of non-essential trace elements like lead and cadmium.