Non-timber forest products (NTFPs) in semi-arid regions of sub-Saharan Africa, play a crucial role in supporting local livelihoods by providing food, income, and raw materials. Particularly in Burkina Faso, the seeds of Senegalia macrostachya (Reichenb. ex DC.) (Zamnè) are highly valued by all social strata due to their nutritional, economic and pharmaceutical importance. However, post-harvest preservation of these seeds remains a major constraint. This study aimed to assess the various post-harvest practices used for S. macrostachya seeds in the rural areas. Data were collected through a structured, interviewer-assisted questionnaire survey. Results revealed that 87.9% of the respondents store their S. macrostachya seeds in polypropylene bags, 52.42% in 20l plastic drums and 24.19% in taditional clay containers. The majority of respondents (99.19%), identified insect infestation as the primary cause of post-harvest losses. Seed preservation is also intended to meet both household consumption and market supply needs. The most commonly employed pest control method is heat-based pre-cooking (90.32% of respondents). In the absence of control measures substancial damage can occur as early as the first week of storage. A better understanding of post-harvest strategies in rural contest is crucial for developing more effective management practises for this important food resource. Through the direct involvement of local farmers, the research seeks to: (i) document current practices, (ii) identify technical and socio-economic bottlenecks, and (iii) provide a baseline for the development of locally adapted, sustainable seed handling and storage strategies.