Autograft tissue currently remains the gold standard of periodontal plastic surgery. It provides excellent predictability, improved long-term outcomes, and superior aesthetics over other treatment options. The amniotic sac encloses the developing foetus through gestation and is composed of amnion and chorion tissues. Amnion basement membrane closely mimics the basement membrane of human oral mucosa. Use of placental allografts in dentistry is a more recent development. The currently available dental form of placental allograft is composed of cryopreserved, dehydrated amnion chorion laminate. Fresh amnion has generally been used .When compared to traditional guided tissue regeneration membranes, placental barriers, such as amnion chroion membranes demonstrate many unique properties including anti-adhesive effects, bacteriostatic properties, wound protection, pain reduction, and epithelialization effects.