The Kom-Sanctuary National Park complex at Gorilla de Mengame located in South Cameroon precisely along the border between Cameroon and Gabon. It has an important exceptional biological biodiversity and is part of the Ngoyla-MINTOM forest massif. In order to improve knowledge on the state of poaching, a survey study was carried out between May and June 2019 with 70 people. Although the results of the study confirm the presence of poaching activity in the area, subsistence hunting is the predominant activity (79%). Three types of stakeholders were identified: primary, secondary and tertiary stakeholders. The respondents find that the most targeted species are duikers (Cephalophus silvicultor, Cephalophus dorsalis, Cephalophus monticola) (59%), pangolins (Manis gigantea) (16%), monkeys (Cercopithecus spp.). Hunters use home-made firearms for small-scale hunting and war weapons for large-scale hunting. The analysis of strengths, weaknesses, opportunities and threats revealed that cross-border poaching and lack of logistical/financial resources are the main threats. The improvement of the population's standard of living through the creation of income-generating activities (IGA) and the involvement of the population in all conservation processes are two essential axes to overcome this problem.