This study is part of the Public Health field, in a transversal descriptive approach, oriented towards reproductive health. It covers the period from January to March 2020.Its objective is to identify the obstacles to the hygienic management of menstruation by high school girls in school. To achieve this goal, we used the survey as a method, the interview was used as a data collection technique, and the interview guide served as a data collection instrument. The Lycéennes constituted for us the study population, the chosen space is the ESENGO Lycée in the town hall of Gemena, Province of Sud-Ubangi in DRC. The sample size for this study is 80 high school girls chosen for convenience.It therefore turns out that age and ignorance combined are at the head of the obstacles identified. Girls who have not reached the age of majority do not have the right to information about their active sex life, talking about it remains a taboo in African societies, even more so than talking about defecation. (Hamdalaye HERE, 2000). Some of them are totally ignorant of the warning signs of menstruation, the lack of prefabricated towels (ignorance of their use and lack of financial means to get them (poverty), hence, resort to the collection of towels (pieces of loincloths, dirty fabrics, etc.), the sanitary facilities even existing within schools, are not used properly (less hygienic conditions, the non-separation of these facilities according to sex, and the absence of a permanent source d water supply ...) can be counted among the obstacles to the unhygienic management of menses at school. This pushes girls to return, to miss class, sometimes to abandon in case of leakage of blood stains on their This can compromise their academic or even professional performance.