This scientific publishing consisted to evoluate the relationship between chemical structure and pharmacological activities of an antipaludical plant “Hygrophilla auriculata ”. The process consisted to a thin layer chromatography using two standards moderns’ drugs with are usually used to treat paludism. Final results revealed factor retention (Rf) similar of quinine sulfate and another equal to the Rf of “L-artem forte”. This result leaded us to conclud that there are similarities in chemical structure of some active ingredient of Hygrophilla auriculata and the modern anticipaludical drugs.
This scientific article had as objective to compare the antipaludic activities and efficiency of Hygrophilla auriculata plant than those of antipaludic modern drugs.
The method consisted to mixture samples of strongly infested blood with Hygrophilla auriculata extracts in some samples and modern anti-malaric dugs in others. After incubation of 24h, 48h and 72h we passed to the parasitologic test.
Obtained result revealed the high efficiency and antimalaric activities of Hygrophilla auriculata crudes extracts than modern anti-malaric drugs such as Quinine and “L-Artem Forte”. This leaded us to conclude that Hygrophilla auriculata plant has a hight antipaludic activity so it must be used to treat people great leak region.
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