The present work aims to study the legal instruments of the Democratic Republic of Congo on the management of chemicals to assess the level of their implementation. This descriptive study covered 31 legal texts, including the Constitution of the Republic, an ordinance-law, eight laws, a framework law, seven ordinances, seven decrees, six decrees and 21 international conventions. The results of the analyzes from the inventory of legal texts show that the country suffers from a problem of the implementation of these different legal texts in the management of chemicals. Thus, for rational management of these products in DR Congo, state authority in control over the life cycle of chemicals (from import to waste management) should be strengthened and a regulatory authority.