Coronary heart disease is dominant and very dangerous disease in the world. Coronary heart disease causes mortality in the world. CHD is very complicated because of many factors that affect this disease. The main factors effects on coronary heart disease are Cholesterol, Diabetes, Depression, and Hypertension. I believe four factors above have tremendous and direct effects on this disease. The rate of death is different according to country, age, and gender. The lack of physical activity is the same in men and women so the rate of hypertension, diabetes, and obesity more common. The main and dangerous point in coronary heart disease occurs when the coronary artery get atherosclerosis. As a result, the fat particles constrict the coronary artery so the blood, oxygen, and sufficient material don't flow to the heart completely. The main purpose of this model is to minimize the risk factors of coronary heart disease. As a result, I believe we can minimize and control this disease by doing more exercise, getting enough sleep, staying away from smoking and drinking, eating low animal products, and more eating fruit and vegetables. This paper goals to review the coronary heart disease and inquire its connections among different factors that must be taken into consideration throughout the process and how to prevent ourselves from risk factors.