[ Corrélation entre la glycémie à jeun et l’HbA1C chez la population diabétique dans la région de la Grande Casablanca ]
Volume 66, Issue 2, May 2023, Pages 345–350
H. Kouame1, A. Morjan2, and Kamal Nbiha3
1 Laboratoire de biochimie, CHU Ibn Rochd de Casablanca, Morocco
2 Laboratoire de biochimie, Hôpital Ibn Rochd, CHU Ibn Rochd, Casablanca, Morocco
3 Laboratoire de biochimie, CHU Ibn Rochd de Casablanca, Morocco
Original language: French
Copyright © 2023 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
In Morocco, according to WHO estimates, the prevalence rate of diabetes in the adult population is 12.4%. This pathology is the cause of more than 12,000 deaths per year. Glycemic control prevents the progression of most complications. Currently, glycated hemoglobin (HbA1c) is the most relevant biological marker for monitoring diabetic patients. The objective of this work is to study the correlation between HbA1c and fasting blood sugar (G0) in diabetic patients at the CHI Ibn Rochd in Casablanca. Fasting blood glucose was sampled on a dry tube and analyzed on the Alinity ® Abbott automaton by an enzymatic method using Hexokinase. The HbA1c assay, taken on tri-potassium EDTA, was carried out by High Performance Liquid Chromatography (HPLC) on an ADAMS TM A1c HA-8180v automaton. Statistical analysis was performed using SPSS software. The correlation between HbA1c and G0 was positive with the Pearson correlation coefficient at r=0.69 and P < 0.001. A 1% rise in the HbA1c value would correspond approximately to a 0.69 g/l rise for the G0 found from the regression curve equation: HbA1C= 4.680 + 1.458 x G0. Our study found a good correlation between fasting blood glucose and HbA1c in Moroccan diabetic adults, which could be useful in clinical practice for better control of glycemic balance.
Author Keywords: Fasting blood glucose, HBA1C, correlation.
Volume 66, Issue 2, May 2023, Pages 345–350
H. Kouame1, A. Morjan2, and Kamal Nbiha3
1 Laboratoire de biochimie, CHU Ibn Rochd de Casablanca, Morocco
2 Laboratoire de biochimie, Hôpital Ibn Rochd, CHU Ibn Rochd, Casablanca, Morocco
3 Laboratoire de biochimie, CHU Ibn Rochd de Casablanca, Morocco
Original language: French
Copyright © 2023 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
In Morocco, according to WHO estimates, the prevalence rate of diabetes in the adult population is 12.4%. This pathology is the cause of more than 12,000 deaths per year. Glycemic control prevents the progression of most complications. Currently, glycated hemoglobin (HbA1c) is the most relevant biological marker for monitoring diabetic patients. The objective of this work is to study the correlation between HbA1c and fasting blood sugar (G0) in diabetic patients at the CHI Ibn Rochd in Casablanca. Fasting blood glucose was sampled on a dry tube and analyzed on the Alinity ® Abbott automaton by an enzymatic method using Hexokinase. The HbA1c assay, taken on tri-potassium EDTA, was carried out by High Performance Liquid Chromatography (HPLC) on an ADAMS TM A1c HA-8180v automaton. Statistical analysis was performed using SPSS software. The correlation between HbA1c and G0 was positive with the Pearson correlation coefficient at r=0.69 and P < 0.001. A 1% rise in the HbA1c value would correspond approximately to a 0.69 g/l rise for the G0 found from the regression curve equation: HbA1C= 4.680 + 1.458 x G0. Our study found a good correlation between fasting blood glucose and HbA1c in Moroccan diabetic adults, which could be useful in clinical practice for better control of glycemic balance.
Author Keywords: Fasting blood glucose, HBA1C, correlation.
Abstract: (french)
Au Maroc, selon les estimations de l’OMS, le taux de prévalence du diabète dans la population adulte est de 12,4 %. Cette pathologie est la cause de plus de 12 000 décès par an. Le contrôle de la glycémique empêche la progression de la plupart des complications. Actuellement, l’hémoglobine glyquée (HbA1c) est le marqueur biologique le plus pertinent pour la surveillance des patients diabétiques. L’objectif de ce travail est d’étudier la corrélation entre HbA1c et glycémie à jeun (G0) chez les patients diabétiques au CHI Ibn Rochd de Casablanca. La Glycémie à jeun a été prélevée sur tube sec et analysée sur l’automate Alinity ®Abbott par une méthode enzymatique à l’Héxokinase. Le dosage de l’HbA1c, prélevé sur EDTA tri-potassique, a été réalisé par Chromatographie Liquide à Haute Performance (HPLC) sur automate ADAMS TM A1c HA-8180v. L’analyse statistique a été effectuée par le logiciel SPSS. La corrélation entre l’HbA1c et la G0 été positive avec le coefficient de corrélation de Pearson à r=0,69 et la P < 0,001. Une élévation de 1 % dans la valeur de l’HbA1c correspondrait approximativement à une élévation de 0,69 g/l pour la G0 trouvée à partir de l’équation de la courbe de régression: HbA1C= 4,680 + 1,458 x G0. Notre étude a permis de trouver une bonne corrélation entre la glycémie à jeun et l’HbA1c chez l’adulte diabétique marocain, ce qui pourrait être utile en pratique clinique permettant un meilleur contrôle de l’équilibre glycémique.
Author Keywords: Glycémie à jeun, HBA1C, corrélation.
How to Cite this Article
H. Kouame, A. Morjan, and Kamal Nbiha, “Correlation between fasting blood glucose and HbA1C in the diabetic population in the Greater Casablanca region,” International Journal of Innovation and Scientific Research, vol. 66, no. 2, pp. 345–350, May 2023.
