Volume 70, Issue 2, January 2024, Pages 81–85
O. Elfadel1, W. Bennane2, and M. Soussi Abdallaoui3
1 Bacteriology-virology laboratory, CHU IBN ROCHD, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
2 Bacteriology-virology laboratory, CHU IBN ROCHD, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
3 Bacteriology-virology laboratory, CHU IBN ROCHD, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
Original language: English
Copyright © 2024 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Introduction: The control and prevention of SARS-COV-2 infection is based on both the respect of individual protection measures and distancing, but also on vaccination. This work aims to evaluate the impact of vaccination on SARS-CoV-2 infection among health professionals at CHUIR and to correlate with the positivity of screening tests. Methods: This is a retrospective study conducted over the period from 15 June 2021 to 1 September 2021. The diagnosis was based on RT-PCR defined and the antigenic test. The healthcare professionals were divided into 2 groups: G1-vaccinated / G2-non vaccinated. The comparison concerned the viral load in positive cases by means of the threshold values (Ct) of RT-PCR and the positivity of the antigenic test. Results: During the study period, 1658 healthcare workers were tested of which 638 were positive, representing a positivity rate of 39%. Clinical symptoms were present in 99% of all positive cases. G1: contains 440 health professionals representing 69% of all positive cases. G2: presents 198 positive non-vaccinated subjects, representing 31%. The average Cts in vaccinated and non-vaccinated subjects was n=24. Conclusion: Understanding the determinants of transmission, including human behavior and vaccine efficacy, is essential for the development of prevention strategies.
Author Keywords: SARS-COV-2, Vaccine, Healthcare workers, RT-PCR, Prevention.
O. Elfadel1, W. Bennane2, and M. Soussi Abdallaoui3
1 Bacteriology-virology laboratory, CHU IBN ROCHD, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
2 Bacteriology-virology laboratory, CHU IBN ROCHD, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
3 Bacteriology-virology laboratory, CHU IBN ROCHD, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
Original language: English
Copyright © 2024 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction: The control and prevention of SARS-COV-2 infection is based on both the respect of individual protection measures and distancing, but also on vaccination. This work aims to evaluate the impact of vaccination on SARS-CoV-2 infection among health professionals at CHUIR and to correlate with the positivity of screening tests. Methods: This is a retrospective study conducted over the period from 15 June 2021 to 1 September 2021. The diagnosis was based on RT-PCR defined and the antigenic test. The healthcare professionals were divided into 2 groups: G1-vaccinated / G2-non vaccinated. The comparison concerned the viral load in positive cases by means of the threshold values (Ct) of RT-PCR and the positivity of the antigenic test. Results: During the study period, 1658 healthcare workers were tested of which 638 were positive, representing a positivity rate of 39%. Clinical symptoms were present in 99% of all positive cases. G1: contains 440 health professionals representing 69% of all positive cases. G2: presents 198 positive non-vaccinated subjects, representing 31%. The average Cts in vaccinated and non-vaccinated subjects was n=24. Conclusion: Understanding the determinants of transmission, including human behavior and vaccine efficacy, is essential for the development of prevention strategies.
Author Keywords: SARS-COV-2, Vaccine, Healthcare workers, RT-PCR, Prevention.
How to Cite this Article
O. Elfadel, W. Bennane, and M. Soussi Abdallaoui, “SARS-CoV-2 vaccine for protecting health professionals: Experience of university hospital of Casablanca,” International Journal of Innovation and Scientific Research, vol. 70, no. 2, pp. 81–85, January 2024.