Volume 32, Issue 2, September 2017, Pages 240–245
BWAMI MUSOMBWA1, J. Roger BYUMANINE NTABAZA2, Alain Maurice SIMBA DELIMENA3, and Octave SHAURI CHIZUNGU4
1 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
2 Assistant 2e Mandat, Institut Supérieur des Techniques Médicales (ISTM)/Uvira, RD Congo
3 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
4 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
Original language: French
Copyright © 2017 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This scientific publishing consisted to evaluate the relationship between chemical structure and pharmacalogical activities of Leucas Martinisensis extracts, an ant-diarrheic plant of Bushi. To arrive there we proceeded by thin layer chromatography using two standards moderns drugs used in diarrheic dieses treatment. Final result revealed spot of analogical retention factor (Rf) with the standards drugs used, such as Cyprofloxacin®, Negrame®. This result leaded us to conclude that there are similarities between some principles ingredients contained in Leucas Martinisensis plant and the witness modern drugs used in treatment of diarrheic dieses.
Author Keywords: activity, structure, Leucas Martinisensis, chromatography, drugs, diarrheic dieses, anti-diarrheic phytochemical.
BWAMI MUSOMBWA1, J. Roger BYUMANINE NTABAZA2, Alain Maurice SIMBA DELIMENA3, and Octave SHAURI CHIZUNGU4
1 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
2 Assistant 2e Mandat, Institut Supérieur des Techniques Médicales (ISTM)/Uvira, RD Congo
3 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
4 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
Original language: French
Copyright © 2017 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
This scientific publishing consisted to evaluate the relationship between chemical structure and pharmacalogical activities of Leucas Martinisensis extracts, an ant-diarrheic plant of Bushi. To arrive there we proceeded by thin layer chromatography using two standards moderns drugs used in diarrheic dieses treatment. Final result revealed spot of analogical retention factor (Rf) with the standards drugs used, such as Cyprofloxacin®, Negrame®. This result leaded us to conclude that there are similarities between some principles ingredients contained in Leucas Martinisensis plant and the witness modern drugs used in treatment of diarrheic dieses.
Author Keywords: activity, structure, Leucas Martinisensis, chromatography, drugs, diarrheic dieses, anti-diarrheic phytochemical.
Abstract: (french)
Le présent travail a consisté à l’évaluation de la relation entre structure chimique et activité pharmacologique des extraits de Leucas Martinisensis, une plante anti-diarrhéique du Bushi. Pour y parvenir, nous avons procédé par une chromatographie comparative sur couche mince en prenant comme témoin deux médicaments modernes dont un antibiotique (Cyprofloxacin®) et un Quinolone (Négrame®), médicaments utilisés dans le traitement moderne des maladies anti-diarrhéiques. Les résultats obtenus ont révélé certains spots de même longueur c'est-à-dire de même Rf que les standards. Ce qui a conduit à la conclusion selon laquelle il existe une similarité entre certains principes actifs de la plante Leucas Martinisensis et ceux des témoins considérés dans le traitement moderne des maladies diarrhéiques.
Author Keywords: Structure, Activité, Leucas Martinisensis, Chromatographie, Médicament, Maladie diarrhéique, Phytochimiotherapie.
How to Cite this Article
BWAMI MUSOMBWA, J. Roger BYUMANINE NTABAZA, Alain Maurice SIMBA DELIMENA, and Octave SHAURI CHIZUNGU, “CONTRIBUTION A L’ETUDE DE LA RELATION STRUCTURE-ACTIVITE DES EXTRAITS AQUEUX ET ETHANOLIQUES DE Leucas Martinisensis : PLANTE MEDICINALE DU BUSHI,” International Journal of Innovation and Scientific Research, vol. 32, no. 2, pp. 240–245, September 2017.
