Volume 16, Issue 1, June 2015, Pages 171–178
Nikhil Das1, Shivamurthy Ravindra2, Mohammed Gulzar Ahmed3, M.R. Vivekananda4, and Sheetal Jain5
1 Post graduate student, Department of Periodontics, Sri Hasanamba Dental College and Hospital, Vidyanagar, P.O. Box 80, Hassan -573 201, Karnataka, India
2 Professor & Head, Department of Periodontics, Sri Hasanamba Dental College and Hospital, Vidyanagar, P.O. Box 80, Hassan -573 201, Karnataka, India
3 Professor and Head, Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, B.G. Nagara, Karnataka, India
4 Reader, Department of Periodontics, Sri Hasanamba Dental College and Hospital, Vidyanagar, P.O. Box 80, Hassan -573 201, Karnataka, India
5 Consultant Periodontist and Assistant Director, Sumukha orofacial and dental care, Hassan, Karnataka, India
Original language: English
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Aim: To evaluate the antibacterial efficacy of green tea extract against two primary colonizers in vitro and to evaluate and compare the antiplaque efficacy in vivo with 0.2% chlorhexidine.
Materials and methods: The minimum inhibitory concentration (MIC) of 0.2% chlorhexidine and green tea were determined in vitro using agar dilution method. A double-blinded, parallel, randomized, 4 day plaque regrowth clinical trial was designed and conducted to determine and compare the antiplaque efficacy of 0.2% chlorhexidine (group1) and green tea (group 2). Thirty subjects (15 males, mean age 31.9 years), participated in the clinical trial, and the plaque index (Silness and Loe 1964) were compared at the 5th day. Statistical analyses for evaluation of plaque growth and comparison between groups were performed by independent t test.
Results: Green tea mouthrinse shows effective antibacterial action against two selected primary colonizers. When compared between groups chlorhexidine hows least MIC. Both groups showed an effective reduction in plaque re-growth. When compared between groups, chlorhexidine showed more plaque control efficacy than green tea, but the results were not statistically significant (p= 0.778).
Conclusion: The findings of this study suggest that green tea shows effective antibacterial against two primary colonizers with an antiplaque action which is comparable with 0.2% chlorhexidine.
Author Keywords: antiplaque, antibacterial, green tea, chlorhexidine, mouthrinse.
Nikhil Das1, Shivamurthy Ravindra2, Mohammed Gulzar Ahmed3, M.R. Vivekananda4, and Sheetal Jain5
1 Post graduate student, Department of Periodontics, Sri Hasanamba Dental College and Hospital, Vidyanagar, P.O. Box 80, Hassan -573 201, Karnataka, India
2 Professor & Head, Department of Periodontics, Sri Hasanamba Dental College and Hospital, Vidyanagar, P.O. Box 80, Hassan -573 201, Karnataka, India
3 Professor and Head, Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, B.G. Nagara, Karnataka, India
4 Reader, Department of Periodontics, Sri Hasanamba Dental College and Hospital, Vidyanagar, P.O. Box 80, Hassan -573 201, Karnataka, India
5 Consultant Periodontist and Assistant Director, Sumukha orofacial and dental care, Hassan, Karnataka, India
Original language: English
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Aim: To evaluate the antibacterial efficacy of green tea extract against two primary colonizers in vitro and to evaluate and compare the antiplaque efficacy in vivo with 0.2% chlorhexidine.
Materials and methods: The minimum inhibitory concentration (MIC) of 0.2% chlorhexidine and green tea were determined in vitro using agar dilution method. A double-blinded, parallel, randomized, 4 day plaque regrowth clinical trial was designed and conducted to determine and compare the antiplaque efficacy of 0.2% chlorhexidine (group1) and green tea (group 2). Thirty subjects (15 males, mean age 31.9 years), participated in the clinical trial, and the plaque index (Silness and Loe 1964) were compared at the 5th day. Statistical analyses for evaluation of plaque growth and comparison between groups were performed by independent t test.
Results: Green tea mouthrinse shows effective antibacterial action against two selected primary colonizers. When compared between groups chlorhexidine hows least MIC. Both groups showed an effective reduction in plaque re-growth. When compared between groups, chlorhexidine showed more plaque control efficacy than green tea, but the results were not statistically significant (p= 0.778).
Conclusion: The findings of this study suggest that green tea shows effective antibacterial against two primary colonizers with an antiplaque action which is comparable with 0.2% chlorhexidine.
Author Keywords: antiplaque, antibacterial, green tea, chlorhexidine, mouthrinse.
How to Cite this Article
Nikhil Das, Shivamurthy Ravindra, Mohammed Gulzar Ahmed, M.R. Vivekananda, and Sheetal Jain, “The Effect of Green Tea Mouthrinse in a 4 Day Plaque Regrowth Model in Vivo and Antibacterial Efficacy in Vitro: A Randomized Controlled Trial,” International Journal of Innovation and Scientific Research, vol. 16, no. 1, pp. 171–178, June 2015.
