[ L'hydatidose humaine dans la région de Rabat (Maroc) : Etude de prévalence et apport du diagnostic sérologique ]
Volume 14, Issue 2, April 2015, Pages 252–258
B. El Mansouri1, Majda Laboudi2, A. SADAK3, and M. Rhajaoui4
1 Department of parasitology, Institut National d'Hygiène, Rabat, Morocco
2 Department of parasitology, Institut National d'Hygiène, Rabat, Morocco
3 Université Mohamed V, Faculté des Sciences Agdal de Rabat, Morocco
4 Department of parasitology, Institut National d'Hygiène, Rabat, Morocco
Original language: French
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: In Morocco, Hydatidosis is a common public health problem, as its impact on the health of the animal and consequently its impact on human health. The aim of our study is to clarify the epidemiological data and to estimate the serological test contribution for hydatidosis diagnosis.
Methods: A retrospective study was undertaken among 392 patients suspect of hydatid cysts collected between January 2000 to December 2010 at the parasitological laboratory of the Institut National d'Hygiène in Rabat region. The serological diagnosis was used simultaneously with Enzyme Linked Immunosorbent Assay and Indirect haemagglutination test for the detection of specific Echinococcus granulosus antibodies.
Results: The overall prevalence of this zoonosis was 37.2 % which women are most affected with 71.2% than 28.8% for men, and sex ratio M / F was 0.5. The prevalence of Echinococcus granulosus varied significantly according to the age and the existence of a surgical history cyst (p <.05). However, gender did not have a significant effect on the prevalence of this pathogen. The kappa coefficient between HAI and ELISA indicated a high level of agreement (0,74). The ultrasound of 181 patients showed that the hydatid cyst involved mainly the liver (68.5%), the kidney (7.7 %) and the lungs (6.1 %).
Conclusion: Hydatidosis disease is a non-immunizing with the possibility of recurrence, which requires further monitoring and surgery should be based primarily on ultrasound and serology.
Author Keywords: Hydatid cyst human, Echinococcus granulosus, Seroprevalence, Serology ELISA, Serology HAI, Morocco.
Volume 14, Issue 2, April 2015, Pages 252–258
B. El Mansouri1, Majda Laboudi2, A. SADAK3, and M. Rhajaoui4
1 Department of parasitology, Institut National d'Hygiène, Rabat, Morocco
2 Department of parasitology, Institut National d'Hygiène, Rabat, Morocco
3 Université Mohamed V, Faculté des Sciences Agdal de Rabat, Morocco
4 Department of parasitology, Institut National d'Hygiène, Rabat, Morocco
Original language: French
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: In Morocco, Hydatidosis is a common public health problem, as its impact on the health of the animal and consequently its impact on human health. The aim of our study is to clarify the epidemiological data and to estimate the serological test contribution for hydatidosis diagnosis.
Methods: A retrospective study was undertaken among 392 patients suspect of hydatid cysts collected between January 2000 to December 2010 at the parasitological laboratory of the Institut National d'Hygiène in Rabat region. The serological diagnosis was used simultaneously with Enzyme Linked Immunosorbent Assay and Indirect haemagglutination test for the detection of specific Echinococcus granulosus antibodies.
Results: The overall prevalence of this zoonosis was 37.2 % which women are most affected with 71.2% than 28.8% for men, and sex ratio M / F was 0.5. The prevalence of Echinococcus granulosus varied significantly according to the age and the existence of a surgical history cyst (p <.05). However, gender did not have a significant effect on the prevalence of this pathogen. The kappa coefficient between HAI and ELISA indicated a high level of agreement (0,74). The ultrasound of 181 patients showed that the hydatid cyst involved mainly the liver (68.5%), the kidney (7.7 %) and the lungs (6.1 %).
Conclusion: Hydatidosis disease is a non-immunizing with the possibility of recurrence, which requires further monitoring and surgery should be based primarily on ultrasound and serology.
Author Keywords: Hydatid cyst human, Echinococcus granulosus, Seroprevalence, Serology ELISA, Serology HAI, Morocco.
Abstract: (french)
Position du problème: Au Maroc, l'hydatidose constitue un réel problème de santé publique, tant par son impact sur la santé de l'animal que par ses conséquences sur la santé humaine. Le but de notre étude est d'éclaircir les données épidémiologiques et d'évaluer l'apport de la sérologie dans le diagnostic de l'hydatidose.
Méthodes: Une étude rétrospective a porté sur 392 patients sans préjugé du statut sérologique colligés au niveau du laboratoire de Parasitologie de l'Institut National d'Hygiène à Rabat entre Janvier 2000 et Décembre 2010. Le dosage des anticorps anti-Echinococcus granulosus a été effectué simultanément par les deux techniques : Enzyme Linked Immunosorbent Assay et Hemagglutination indirecte.
Résultats: Le taux de séropositivité de cette zoonose est de 37,2%, dont les femmes sont les plus touchées avec une fréquence de 71.2% contre 28.8% chez les hommes, et un sex-ratio H/F de 0,5. Une différence significative a été observée entre l'âge, l'existence d'un antécédent chirurgicale et la positivité de la sérologie du kyste hydatique (p<0,05). Cependant, aucune différence significative n'a été trouvé entre le sexe et la prévalence de cette pathogène. Le calcul du coefficient Kappa entre le test HAI et l'ELISA a indiqué un grand niveau de concordance (0,74). L'échographie de 181 patients a montré que le site de prédilection du kyste hydatique est au niveau du foie (68,5%), suivie du rein (7,7%) et des poumons (6,1%).
Conclusion: L'hydatidose est une maladie non immunisante avec possibilité de récidive, qui nécessite une surveillance ultérieure des opérés et doit reposer non seulement sur l'échographie mais aussi sur la sérologie.
Author Keywords: Kyste hydatique humain, Echinococcus granulosus, Séroprévalence, Sérologie ELISA, Sérologie HAI, Maroc.
How to Cite this Article
B. El Mansouri, Majda Laboudi, A. SADAK, and M. Rhajaoui, “Hydatidosis human in Rabat region (Morocco): study of prevalence and contribution of serological diagnosis,” International Journal of Innovation and Scientific Research, vol. 14, no. 2, pp. 252–258, April 2015.
