Volume 9, Issue 2, September 2014, Pages 246–254
Lahcen Elmoumou1, T. Madad2, K. Sahmoudi3, R. Hazime4, Naoufal Mtioui5, Mohamed Zamd6, M. Riyad7, Benyounes Ramdani8, F. Seghrouchni9, and Hassan Fellah10
1 Immunology Laboratory, Faculty of Medicine and Pharmacy, Casablanca, Morocco
2 Department of Nephrology, CHU Ibn Rushed of Casablanca, Morocco
3 Immunology Laboratory, National Institute of Hygiene, Rabat, Morocco
4 Laboratory of Biological Analyzes, Immunology Unit, CHU Mohammed VI, Marrakech, Morocco
5 Department of Nephrology, CHU Ibn Rushed of Casablanca, Morocco
6 Department of Nephrology, CHU Ibn Rushed of Casablanca, Morocco
7 Doctoral Studies Center in Health Sciences: Immunology, Faculty of Medicine and Pharmacy of Casablanca, Morocco
8 Department of Nephrology, CHU Ibn Rushed of Casablanca, Morocco
9 Immunology Laboratory, National Institute of Hygiene, Rabat, Morocco
10 Immunology Laboratory, Faculty of Medicine and Pharmacy, Casablanca, Morocco
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
End stage renal disease (ESRD) is characterized by disorders of both the innate and adaptive systems.
No study is available on disturbance of immune system in ESRD Moroccans patients under dialysis treatment. The aim of this study is to describe the immune status in these patient groups.
Our results show the need for a further study in our patients, who are in a state of chronic inflammation following activation of complement, and immune dysfunction leading to impaired function of cells T, B and NK, accompanied by decreased production of antibodies.
Understanding the mechanisms behind the immune dysfunction in ESRD generates a perspective to improve lifestyle and reduce mortality in this group of patients.
Author Keywords: Immune status, uremic patients, antibodies.
Lahcen Elmoumou1, T. Madad2, K. Sahmoudi3, R. Hazime4, Naoufal Mtioui5, Mohamed Zamd6, M. Riyad7, Benyounes Ramdani8, F. Seghrouchni9, and Hassan Fellah10
1 Immunology Laboratory, Faculty of Medicine and Pharmacy, Casablanca, Morocco
2 Department of Nephrology, CHU Ibn Rushed of Casablanca, Morocco
3 Immunology Laboratory, National Institute of Hygiene, Rabat, Morocco
4 Laboratory of Biological Analyzes, Immunology Unit, CHU Mohammed VI, Marrakech, Morocco
5 Department of Nephrology, CHU Ibn Rushed of Casablanca, Morocco
6 Department of Nephrology, CHU Ibn Rushed of Casablanca, Morocco
7 Doctoral Studies Center in Health Sciences: Immunology, Faculty of Medicine and Pharmacy of Casablanca, Morocco
8 Department of Nephrology, CHU Ibn Rushed of Casablanca, Morocco
9 Immunology Laboratory, National Institute of Hygiene, Rabat, Morocco
10 Immunology Laboratory, Faculty of Medicine and Pharmacy, Casablanca, Morocco
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
End stage renal disease (ESRD) is characterized by disorders of both the innate and adaptive systems.
No study is available on disturbance of immune system in ESRD Moroccans patients under dialysis treatment. The aim of this study is to describe the immune status in these patient groups.
Our results show the need for a further study in our patients, who are in a state of chronic inflammation following activation of complement, and immune dysfunction leading to impaired function of cells T, B and NK, accompanied by decreased production of antibodies.
Understanding the mechanisms behind the immune dysfunction in ESRD generates a perspective to improve lifestyle and reduce mortality in this group of patients.
Author Keywords: Immune status, uremic patients, antibodies.
How to Cite this Article
Lahcen Elmoumou, T. Madad, K. Sahmoudi, R. Hazime, Naoufal Mtioui, Mohamed Zamd, M. Riyad, Benyounes Ramdani, F. Seghrouchni, and Hassan Fellah, “Immune status among Moroccans uremic patients,” International Journal of Innovation and Scientific Research, vol. 9, no. 2, pp. 246–254, September 2014.
