Treatment failures and the more high cost of treatment of infections caused by resistant bacteria called to find other care alternatives. This study was initiated to evaluate the antibacterial activity of the aqueous extract from Hunteria ebunea stem bark on multi-resistant strains. The methods of diffusion in agar and liquid media were used for susceptibility testing and MIC and MBC determination. The tests were performed on four multi-resistant strains isolated from patients and three reference strains were used as control. The minimum inhibitory concentrations of the extracts ranged from 3,12 mg/mL and 50 mg/mL and minimum bactericidal concentrations between 25 mg/mL and 100 mg/mL. The results obtained show that all the bacterial strains are sensitive to aqueous total extract. This extract is bactericidal on S. aureus, E. coli and bacteriostatic on P. aeruginosa. This migth justify the use of Hunteria eburnea trunk back in the treatment of various infections in traditional settings.

In Ivory Coast, the barks of Enantia polycarpa and the leaves of Bersama abissynica, two medicinal species are usually used by populations to treat various diseases such as malaria, diarrheas and cutaneous diseases. To estimate the biological dangers connected to the frequent use of these medicinal plants, the current study was undertaken with objective to evaluate the cytotoxic activity of 70% ethanolic extract on Human Foreskin Fibroblast (HFF) cells in the in vitro culture. 70% ethanolic extract of plants were prepared and the colorimetric test of the MTT is used to evaluate the toxicity of these extracts. The results proved that the ethanolic extract of Enantia polycarpa showed the biggest yield (56,4%). The 70 % éthanlic extract of Bersama abissynica is not cytotoxic at 1000 µg / ml concentration, but mitogen. Our study has shown that the ethanolic extract of Bersama abissynica stimulates HFF cells in division growth (268%). While Enantia polycarpa seems cytotoxic on HFF cells at 1000 µg / ml concentration (36% of viability confluents cells and 55% of viability cells in division). Such results well support that the moderate use of these medicinal plants only represents a limited risk in terms of toxicity. However, follow-up studies must be envisaged in order to determine the chemical compounds responsible of the cytotoxic effect at Enantia polycarpa and those responsible for the mitogen effect at Bersama abissynica.