Volume 31, Issue 1, June 2017, Pages 26–30
J. Roger BYUMANINE NTABAZA1
1 Assistant 2e Mandat, Institut Supérieur des Techniques Médicales (ISTM)/Uvira, RD Congo
Original language: French
Copyright © 2017 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This scientific work consisted to the evaluation of relationship between chemical structures and pharmacological activities of Kalanchoe crenata extracts. An antdiarrheic plant founded in Bushi. To arrive there we proceeded by the thin layer chromatography using two standards modems drugs used in diarrhea treatment. Final results revealed spots of analogical retention factor (Rf) with the standards used. Such as ciprofloxacin®, Negrame®. This leaded us to conclude that there are similarities between some principles ingredients contained in Kalanchoe crenata and the witness moderns drugs used in diarrhea treatment.
Author Keywords: Relationship chemical structure, Pharmacological activity, Kalanchoe crenata drugs, Chromatography, Antdiarrheic phytochemical treatment.
J. Roger BYUMANINE NTABAZA1
1 Assistant 2e Mandat, Institut Supérieur des Techniques Médicales (ISTM)/Uvira, RD Congo
Original language: French
Copyright © 2017 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
This scientific work consisted to the evaluation of relationship between chemical structures and pharmacological activities of Kalanchoe crenata extracts. An antdiarrheic plant founded in Bushi. To arrive there we proceeded by the thin layer chromatography using two standards modems drugs used in diarrhea treatment. Final results revealed spots of analogical retention factor (Rf) with the standards used. Such as ciprofloxacin®, Negrame®. This leaded us to conclude that there are similarities between some principles ingredients contained in Kalanchoe crenata and the witness moderns drugs used in diarrhea treatment.
Author Keywords: Relationship chemical structure, Pharmacological activity, Kalanchoe crenata drugs, Chromatography, Antdiarrheic phytochemical treatment.
Abstract: (french)
Le présent travail consistait à l’évaluation de la relation entre la structure chimique et l’activité pharmacologique des extraits de Kalanchoe crenata, une plante anti-diarrhéique utilisée au Bushi. Pour y parvenir, nous avons procédé à une chromatographie comparative sur couche mince en prenant comme standard deux médicaments modernes dont un Antibiotique (cyprofloxacin) et un Quinolone (Negrame ®), médicaments utilisés dans le traitement de la diarrhé. Les résultats obtenus ont révélé certains spots de même longueur que ceux des standards. Ce qui a conduit à conclure l’existence d’une similarité entre certains principes actifs de la plante Kalanchoe crenata et ceux des témoins considérés dans le traitement moderne de la diarrhée.
Author Keywords: Relation structure activité, Kalanchoe crenata, Médicament, Chromatographie, Anti-diarrhéique, Phytochimiothérapie.
How to Cite this Article
J. Roger BYUMANINE NTABAZA, “CONTRIBUTION A L’ETUDE DE LA RELATION STRUCTURE-ACTIVITE DES EXTRAITS AQUEUX ET ETHANOLIQUE DE KALANCHOE CRENATA : PLANTE MEDICINALE AU BUSHI,” International Journal of Innovation and Scientific Research, vol. 31, no. 1, pp. 26–30, June 2017.
