[ Adénosarcome utérin: étude de 5 cas ]
Volume 26, Issue 1, August 2016, Pages 255–259
Zied Benzarti1, Ines Zemni2, Montassar Ghalleb3, Tarek Damak4, Maha Driss5, Monia Hechiche6, and Khaled Rahal7
1 Service de chirurgie carcinologique, Institut Salah Azaeiz, Tunis, Tunisia
2 Service de chirurgie carcinologique, Institut Salah Azaeiz, Tunis, Tunisia
3 Service de chirurgie carcinologique, Institut Salah Azaeiz, Tunis, Tunisia
4 Service de chirurgie carcinologique, Institut Salah Azaiez, Boulevard 9 Avril, 1006 Tunis, Tunisia
5 Service d’anatomo-pathologie, Institut Salah Azaeiz, Tunis, Tunisia
6 Service de chirurgie carcinologique, Institut Salah Azaiez, Boulevard 9 Avril, 1006 Tunis, Tunisia
7 Service de chirurgie carcinologique, Institut Salah Azaiez, Boulevard 9 Avril, 1006 Tunis, Tunisia
Original language: French
Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Introduction: The uterine adenosarcome is a rare tumor, is composed of a benign glandular component and a sarcomatous stroma. It’s characterized by its rarity, difficulties in both diagnostic and therapeutic care. Patients and methods: A retrospective review, from 1993 to 2013, of five cases of uterine adenosarcome diagnosed and treated at the institute Salah Azaeiz. Results: Patients’ mean age was 54.4 years. Three patients were postmenopausal. Vaginal bleeding was the most common presenting symptom. Physical examination combined with pelvic ultrasonography found a uterus increased in size. The diagnosis was made by biopsy curettage, biopsy of the polyp or study of the surgical specimen. Three patients underwent surgery. Four patients were in FIGO stage I, one patient in stage IV. Two patients benefited from adjuvant radiotherapy and one patient benefited only from chemotherapy. After a mean follow-up of 54 months, one patient was in complete remission. Pelvic local recurrence and metastasis in inguinal nodes were observed in two patients. Conclusion: Surgery is often sufficient. Its prognosis is relatively favorable.
Author Keywords: Adenosarcoma, Uterus, Surgery, Radiotherapy, Chemotherapy.
Volume 26, Issue 1, August 2016, Pages 255–259
Zied Benzarti1, Ines Zemni2, Montassar Ghalleb3, Tarek Damak4, Maha Driss5, Monia Hechiche6, and Khaled Rahal7
1 Service de chirurgie carcinologique, Institut Salah Azaeiz, Tunis, Tunisia
2 Service de chirurgie carcinologique, Institut Salah Azaeiz, Tunis, Tunisia
3 Service de chirurgie carcinologique, Institut Salah Azaeiz, Tunis, Tunisia
4 Service de chirurgie carcinologique, Institut Salah Azaiez, Boulevard 9 Avril, 1006 Tunis, Tunisia
5 Service d’anatomo-pathologie, Institut Salah Azaeiz, Tunis, Tunisia
6 Service de chirurgie carcinologique, Institut Salah Azaiez, Boulevard 9 Avril, 1006 Tunis, Tunisia
7 Service de chirurgie carcinologique, Institut Salah Azaiez, Boulevard 9 Avril, 1006 Tunis, Tunisia
Original language: French
Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction: The uterine adenosarcome is a rare tumor, is composed of a benign glandular component and a sarcomatous stroma. It’s characterized by its rarity, difficulties in both diagnostic and therapeutic care. Patients and methods: A retrospective review, from 1993 to 2013, of five cases of uterine adenosarcome diagnosed and treated at the institute Salah Azaeiz. Results: Patients’ mean age was 54.4 years. Three patients were postmenopausal. Vaginal bleeding was the most common presenting symptom. Physical examination combined with pelvic ultrasonography found a uterus increased in size. The diagnosis was made by biopsy curettage, biopsy of the polyp or study of the surgical specimen. Three patients underwent surgery. Four patients were in FIGO stage I, one patient in stage IV. Two patients benefited from adjuvant radiotherapy and one patient benefited only from chemotherapy. After a mean follow-up of 54 months, one patient was in complete remission. Pelvic local recurrence and metastasis in inguinal nodes were observed in two patients. Conclusion: Surgery is often sufficient. Its prognosis is relatively favorable.
Author Keywords: Adenosarcoma, Uterus, Surgery, Radiotherapy, Chemotherapy.
Abstract: (french)
Introduction: L’adénosarcome utérin est une tumeur extrêmement rare (8 % des sarcomes utérins), caractérisée par la prolifération d’une composante mésenchymateuse maligne et une composante épithéliale bénigne. Il est reconnu par sa difficulté de prise en charge diagnostique et thérapeutique. Moyens d’étude: Il s’agit d’une étude rétrospective de 5 cas d’adénosarcome utérin pris en charge au sein de l’institut Salah Azaeiz de Tunis, entre 1993 et 2013, avec revue de la littérature internationale. Résultats: L’âge moyen des patientes était de 54,4 ans. Trois patientes étaient ménopausées. Les métrorragies étaient le motif de consultation le plus fréquent. L’examen gynécologique trouvait souvent un polype accouché par le col (3 cas) et un utérus augmenté de taille. L’échographie pelvienne montrait souvent un utérus augmenté de taille et une lésion intra-utérine d’aspect hétérogène. Les moyens de diagnostic étaient le curetage biopsique, la biopsie du polype accouché par le col ou l’étude de la pièce opératoire. Le traitement chirurgical a été réalisé chez 3 patientes. Quatre patientes étaient classées stade I de FIGO et une seule classée stade IV. Deux patientes ont bénéficié d’une radiothérapie adjuvante. Une chimiothérapie a été prescrite chez la patiente ayant des métastases hépatique d’emblée. Après un recul moyen était de 54 mois, une patiente était en rémission complète. Une récidive locorégionale pelvienne et une métastase au niveau des ganglions inguinaux étaient observées chez les deux autres patientes opérées. Conclusion: Le traitement chirurgical seul est souvent satisfaisant. Son pronostic est relativement favorable.
Author Keywords: Adénosarcome, Utérus, Chirurgie, Radiothérapie, Chimiothérapie.
How to Cite this Article
Zied Benzarti, Ines Zemni, Montassar Ghalleb, Tarek Damak, Maha Driss, Monia Hechiche, and Khaled Rahal, “Adenosarcoma of the Uterus: a clinicopathologic analysis of 5 cases,” International Journal of Innovation and Scientific Research, vol. 26, no. 1, pp. 255–259, August 2016.
