[ Une analyse biostatistique de l'effet du médicament 6-mercaptopurine sur le temps de survie d'un échantillon aléatoire de patients atteint de leucémie aigue ]
Volume 13, Issue 2, February 2015, Pages 679–688
Moulay El Mehdi Falloul1
1 Ph.D candidate in applied economics and finance, Hassan II University of Mohammedia, Mohammedia, Morocco
Original language: French
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Our goal is to determine whether and how the drug affects the survival time, comparing the survival curves of two groups of 21 patients, the first being treated, and the second component the control group. In the 6-MP group, only 9 patients showed a relapse, while 12 others were "censored" (cure or lost sight of by the leaders of the study). In the control group all relapsed. This is achieved by using the survival model and the Kaplan Meier.
Author Keywords: Biostatistical analysis, 6-mercaptopurine, survival time, acute leukemia.
Volume 13, Issue 2, February 2015, Pages 679–688
Moulay El Mehdi Falloul1
1 Ph.D candidate in applied economics and finance, Hassan II University of Mohammedia, Mohammedia, Morocco
Original language: French
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Our goal is to determine whether and how the drug affects the survival time, comparing the survival curves of two groups of 21 patients, the first being treated, and the second component the control group. In the 6-MP group, only 9 patients showed a relapse, while 12 others were "censored" (cure or lost sight of by the leaders of the study). In the control group all relapsed. This is achieved by using the survival model and the Kaplan Meier.
Author Keywords: Biostatistical analysis, 6-mercaptopurine, survival time, acute leukemia.
Abstract: (french)
Notre but est de déterminer si et comment le médicament influence le temps de survie, en comparant les courbes de survie de deux groupes de 21 patients, le premier étant traité, et le second constituant le groupe de contrôle. Dans le groupe 6-MP, seuls 9 des patients ont montré une rechute, tandis que les 12 autres ont été "censurés" (guérison ou perdus de vue par les responsables de l'étude). Dans le groupe de contrôle tous ont rechuté. Cette est réalisé en utilisant le modèle de survie et l'estimateur de Kaplan Meier.
Author Keywords: analyse biostatistique, 6-mercaptopurine, temps de survie, leucémie aigue.
How to Cite this Article
Moulay El Mehdi Falloul, “A Biostatistical analysis of the effect of 6-mercaptopurine drug on the survival time of a random sample of patients suffering from acute leukemia,” International Journal of Innovation and Scientific Research, vol. 13, no. 2, pp. 679–688, February 2015.
