Volume 32, Issue 2, September 2017, Pages 234–239
Jean Roger BYUMANINE NTABAZA1, BWAMI MUSOMBWA2, Octave SHAURI CHIZUNGU3, and Alain Maurice SIMBA DELIMENA4
1 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
2 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
3 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
4 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
Original language: French
Copyright © 2017 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This scientific publishing consisted to the evaluation of relationship between chemical structures and pharmacological activities of Spilanthes Mauritiana extracts, an antdiarrheic plant founded in Bushi. To arrive there we proceeded by the thin layer chromatography using two standards moderns drugs used in diarrhea treatment. Final results revealed spots of analogical retention factor (Rf) with the standards used, such as ciprofloxacin ®, Negrame®. This leaded us to conclude that there are similarities between some principles ingredients contained in Spilanthes Mauritiana and the witness moderns drugs used in diarrhea treatment.
Author Keywords: Relationship chemical structure, Pharmacological activity, Spilanthes Mauritiana, drugs, Chromatography, Antdiarrheic, phytochemical treatment.
Jean Roger BYUMANINE NTABAZA1, BWAMI MUSOMBWA2, Octave SHAURI CHIZUNGU3, and Alain Maurice SIMBA DELIMENA4
1 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
2 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
3 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
4 Institut Supérieur Technique, Commerciale et Economique (ISTCE) Bukavu/Uvira, RD Congo
Original language: French
Copyright © 2017 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
This scientific publishing consisted to the evaluation of relationship between chemical structures and pharmacological activities of Spilanthes Mauritiana extracts, an antdiarrheic plant founded in Bushi. To arrive there we proceeded by the thin layer chromatography using two standards moderns drugs used in diarrhea treatment. Final results revealed spots of analogical retention factor (Rf) with the standards used, such as ciprofloxacin ®, Negrame®. This leaded us to conclude that there are similarities between some principles ingredients contained in Spilanthes Mauritiana and the witness moderns drugs used in diarrhea treatment.
Author Keywords: Relationship chemical structure, Pharmacological activity, Spilanthes Mauritiana, drugs, Chromatography, Antdiarrheic, phytochemical treatment.
Abstract: (french)
Le présent travail consistait à l’évaluation de la relation entre la structure chimique et l’activité pharmacologique des extraits de Spilanthes Mauritiana, une plante anti-diarrhéique utilisée au Bushi. Pour y parvenir, nous avons procédé par une chromatographie comparative sur couche mince en prenant comme standard deux médicaments modernes dont un Antibiotique (Cyprofloxacin®) et un Quinolone (Negrame ®), médicaments utilisés dans le traitement des maladies diarrhéiques. Les résultats obtenus ont révélé certains spots de même longueur, même forme et donc même coefficient de rétention (Rf) que les standards. Ce qui a conduit à conclure l’existence d’une similarité entre certains principes actifs de la plante Spilanthes Mauritiana et ceux des témoins considérés dans le traitement moderne des maladies diarrhéiques.
Author Keywords: Relation structure activité, Spilanthes Mauritiana, Médicament, Chromatographie, Anti-diarrhéique, Phytochimiothérapie.
How to Cite this Article
Jean Roger BYUMANINE NTABAZA, BWAMI MUSOMBWA, Octave SHAURI CHIZUNGU, and Alain Maurice SIMBA DELIMENA, “CONTRIBUTION A L’ETUDE DE LA RELATION STRUCTURE-ACTIVITE DES EXTRAITS AQUEUX ET ETHANOLIQUE DE SPILANTHES MAURITIANA : PLANTE MEDICINALE DU BUSHI,” International Journal of Innovation and Scientific Research, vol. 32, no. 2, pp. 234–239, September 2017.
